Hyperbaric Oxygen Therapy
Hyperbaric Oxygen Therapy (HBOT):
Consists of breathing various concentrations of oxygen in a pressurized chamber. This stimulates cellular healing and optimizes recovery for a variety of conditions.​
​​
The Recent Research behind HBOT and PPCS:
More recent research looking at low dose HBOT for mTBI and chronic PPCS (persistent post concussive symptoms) has shown improvements in cognition, PTSD, and overall symptoms. Specifically, significant improvement in memory, executive functions and information processing speed. Furthermore a number of studies have shown HBOT can induce improved blood flow, brain function, and brain microstructure:
Study Citations:
Harch PG. Systematic Review and Dosage Analysis: Hyperbaric Oxygen Therapy Efficacy in Mild Traumatic Brain Injury Persistent Postconcussion Syndrome. Front Neurol. 2022 Mar 17;13:815056. doi: 10.3389/fneur.2022.815056. PMID: 35370898; PMCID: PMC8968958.
Harch PG, Andrews SR, Rowe CJ, Lischka JR, Townsend MH, Yu Q, Mercante DE. Hyperbaric oxygen therapy for mild traumatic brain injury persistent postconcussion syndrome: a randomized controlled trial. Med Gas Res. 2020 Jan-Mar;10(1):8-20. doi: 10.4103/2045-9912.279978. PMID: 32189664; PMCID: PMC7871939.
Schimmel S, El Sayed B, Lockard G, Gordon J, Young I, D'Egidio F, Lee JY, Rodriguez T, Borlongan CV. Identifying the Target Traumatic Brain Injury Population for Hyperbaric Oxygen Therapy. Int J Mol Sci. 2023 Sep 27;24(19):14612. doi: 10.3390/ijms241914612. PMID: 37834059; PMCID: PMC10572450.
Harch PG, Andrews SR, Fogarty EF, Amen D, Pezzullo JC, Lucarini J, Aubrey C, Taylor DV, Staab PK, Van Meter KW. A phase i study of low-pressure hyperbaric oxygen therapy for blast-induced post-concussion syndrome and post-traumatic stress disorder. Journal of Neurotrauma. 2012;29(1):168–185. doi: 10.1089/neu.2011.1895.
Boussi-Gross, R., Golan, H., Fishlev, G., Bechor, Y., Volkov, O., Bergan, J., Friedman, M., Hoofien, D., Shlamkovitch, N., Ben-Jacob, E., & Efrati, S. (2013). Hyperbaric oxygen therapy can improve post concussion syndrome years after mild traumatic brain injury - Randomized prospective trial. PLoS One, 8(11).
Tal S, Hadanny A, Berkovitz N, Sasson E, Ben-Jacob E, Efrati S. Hyperbaric oxygen may induce angiogenesis in patients suffering from prolonged post-concussion syndrome due to traumatic brain injury. Restorative Neurology and Neuroscience. 2015;33(6):943–951.
Hadanny A, Abbott S, Suzin G, Bechor Y, Efrati S. Effect of hyperbaric oxygen therapy on chronic neurocognitive deficits of posttraumatic brain injury patients: Retrospective analysis. British Medical Journal Open. 2018;8(9):1–9. doi: 10.1136/bmjopen-2018-023387
Tal, S., Hadanny, A., Sasson, E., Suzin, G., Efrati, S. (2017). Hyperbaric oxygen therapy can induce angiogenesis and regeneration of nerve fibers in traumatic brain injury patients. Frontiers in Human Neuroscience, 11. 10.3389/fnhum.2017.00508
Further information can be found at:
https://hbot.com/conditions/traumatic-brain-injury/
https://www.ihausa.org/resources.html
​​​​​